Anti-Human CD243 (ABCB1) APC_中国教育装备采购网

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 Anti-Human CD243 (ABCB1) APC
  • Anti-Human CD243 (ABCB1) APC
  • Anti-Human CD243 (ABCB1) APC

    参考价格: ¥0.00
    适用范围:全领域
    所在地区:
    上架时间:2011年09月19日
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    Anti-Human CD243 (ABCB1) APCAlso known as: P-glycoprotein-1, MDR1 Clone: UIC2 RUO: For Research Use Only

    Description: This monoclonal antibody reacts with human Multidrug Resistant (MDR)-1, which is also known as P-glycoprotein (Pgp) and CD243. A 170-kDa transmembrane protein, MDR-1 is an ATP-dependent efflux pump for lipophilic compounds, including anti-cancer drugs. Expression of MDR-1 has been shown to correlate with multidrug resistance. In fact, tumor resistance to chemotherapy has been linked to MDR-1 expression in many cancers. MDR-1 is expressed in a variety of tissues, including the brain, kidney, liver, pancreas, and testes. Within the immune system, this molecule can be found on normal T, B, and natural killer cells, but not on monocytes.

    This antibody has been reported to inhibit MDR1-mediated efflux.