上海经科化学科技有限公司

 Anti-Human CD162 (PSGL-1) PerCP-eFluor? 710
  • Anti-Human CD162 (PSGL-1) PerCP-eFluor? 710
  • Anti-Human CD162 (PSGL-1) PerCP-eFluor? 710

    参考价格: ¥0.00
    适用范围:全领域
    所在地区:
    上架时间:2011年09月19日
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    Anti-Human CD162 (PSGL-1) PerCP-eFluor? 710Clone: FLEG RUO: For Research Use Only

    Description: This FLEG monoclonal antibody recognizes human CD162, which is also known as P-selectin glyocoprotein ligand-1 (PSGL-1). This 120-kDa protein exists as a homodimer on the surface of monocytes, neutrophils, granulocytes, peripheral T cells, some B cells, and a subset of CD34+ hematopoietic progenitor cells (HPCs) in the bone marrow. CD162 binds CD62P (P-selectin), CD62E (E-selectin), and CD62L (L-selectin) to mediate leukocyte interactions with each other as well as with activated platelets and endothelium. Thus, CD162 plays a critical role in leukocyte adhesion and rolling. Furthermore, the binding of CD162 to P-selectin on HPCs has been demonstrated to inhibit hematopoiesis. Studies have also demonstrated CD162 as the receptor for enterovirus 71.