上海经科化学科技有限公司

 Anti-Human Podocalyxin PE
  • Anti-Human Podocalyxin PE
  • Anti-Human Podocalyxin PE

    参考价格: ¥0.00
    适用范围:全领域
    所在地区:
    上架时间:2011年09月19日
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    Anti-Human Podocalyxin PEAlso known as: Gp200 Clone: B34D1.3 RUO: For Research Use Only

    Description: The monoclonal antibody B34D1.3 recognizes human podocalyxin, a protein expressed on undifferentiated human embryonic stem cells (ES), embryonic carcinoma cells (EC), and embryonic germ cells (EG). Podocalxyin is a heavily glycosylated cell adhesion protein with homology to CD34 and endoglycan. It was first identified on kidney podocytes, and then found to be upregulated in a variety of human cancers such as breast and prostate cancer. Like other stem cell-specific markers, the epitope recognized by the B34D1.3 antibody is lost upon cell differentiation.

    The B34D1.3 antibody recognizes the ectodomain of podocalyxin, which is a different epitope from the Tra-1-60 and Tra-1-81 monoclonal antibodies. While Tra1-60 has been found to react with a sialidase-sensitive epitope, the epitope recognized by Tra1-81 has not been fully defined.