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Anti-Bovine Gαo Protein-Purified

Anti-Bovine Gαo Protein-Purified

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Anti-Bovine Gαo Protein-PurifiedMonoclonal AntibodyProd. No.: G105 Clone: 2A Isotype: Mouse IgG1 Conc.: 0.1 mg/ml Pkg. Size: 0.25 mg Storage: 2-8°C

Anti-Bovine Gαo Protein-Purified
Monoclonal Antibody
Prod. No.:   G105
Clone:       2A
Isotype:     Mouse IgG1
Conc.:       0.1 mg/ml
Pkg. Size:   0.25 mg
Storage:     2-8°C

Description
Specificity:
The anti Gαo protein antibody 2A recognizes Gαo protein from bovine, human, rat and mouse.

Antigen Distribution:
Antibody 2A reacts with bovine Gαo protein. Antibody showed 70% reactivity in human, 61% in rat and 54% in mouse of the bovine reactivity.

Background:
Heterotrimeric G proteins, composed of Gα and Gβγ subunits, transmit signals from cell surface receptors to cellular effector enzymes and ion channels. The Gαo protein is the most abundant Gα subtype in the nervous system, but it is also found in the heart. Its function is not completely known, although it is required for regulation of N-type Ca2+ channels in GH3 cells and also interacts with GAP43, a major protein in growth cones, suggesting a role in neuronal pathfinding.

Known Species Cross Reactivity: Ms+, Hu+, Rt+, Bov+
Host Species
Mouse
Immunogen
Purified Recombinant Bovine Gαo Protein (>98%)
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Reported Applications
IHC (NBF/Par.), IP, WB

References
1. Li, X. et al. (1995) J. Neurochemistry 64:1107
Related Products
Anti-Gαo Protein-Biotin (Leinco Prod. No.: G106)
Anti-Gαo Protein-Agarose (Leinco Prod. No.: G107)

Products are for research use only. Not for use in diagnostic or therapeutic procedures