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 Anti-Human Phosphodiesterase V
  • Anti-Human Phosphodiesterase V
  • Anti-Human Phosphodiesterase V

    参考价格: ¥0.00
    适用范围:全领域
    所在地区:
    上架时间:2011年12月21日
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    详细说明

    Anti-Human Phosphodiesterase V(Phosphodiesterase V)
    Purified
    (PDE-5)
    Monoclonal Antibody
    Prod. No.: P164
    Clone: 29.29
    Isotype: Mouse IgG1
    Conc.: 0.5 mg/ml
    Pkg. Size: 0.1mg
    Storage: 2-8°C

    Anti-Human Phosphodiesterase V(Phosphodiesterase V)
    Purified
    (PDE-5)
    Monoclonal Antibody
    Prod. No.: P164
    Clone: 29.29
    Isotype: Mouse IgG1
    Conc.: 0.5 mg/ml
    Pkg. Size: 0.1mg
    Storage: 2-8°C

    Description
    Specificity:
    Mouse Anti-Human Phosphodiesterase V (Phosphodiesterase V) (Clone 29.29) recognizes an epitope on Human Phosphodiesterase V. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

    Background:

    Phosphodiesterases (PDEs) are a superfamily of enzymes that degrade the intracellular second messengers cyclic AMP and cyclic GMP. These enzymes are essential regulators of cyclic nucleotide signaling with diverse physiological functions. PDEs are drug targets for the treatment of disease states including heart failure, depression, asthma, inflammation and erectile dysfunction. Of the 12 PDE gene families, cGMP specific PDE5 carries out the principal cGMP hydrolyzing activity.1,2

    Known Species Cross Reactivity: Hu+

    Host Species
    Mouse
    Formulation
    This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
    Storage and Stability
    This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
    Reported Applications
    WB
     
    References
    1. Piazza, Gary, et al. (2001) Cancer Research 61:3961-3968
    2. Sung, Byung-Je et al. (1002) Nature 425:98-102