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 Anti-Mouse CD120α
  • Anti-Mouse CD120α
  • Anti-Mouse CD120α

    参考价格: ¥0.00
    适用范围:全领域
    所在地区:
    上架时间:2011年12月21日
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    详细说明

    Anti-Mouse CD120α
    Purified Low Endotoxin Functional Formulation
    (TNFR1)
    Monoclonal Antibody
    Prod. No.: T245
    Clone: 55R-593
    Isotype: Armenian Hamster IgG
    Conc.: 1.0 mg/ml
    Pkg. Size: Custom, 50 μg, 500 μg

    Anti-Mouse CD120α
    Purified Low Endotoxin Functional Formulation
    (TNFR1)
    Monoclonal Antibody
    Prod. No.: T245
    Clone: 55R-593
    Isotype: Armenian Hamster IgG
    Conc.: 1.0 mg/ml
    Pkg. Size: Custom, 50 µg, 500 µg

    Description
    Specificity:
    Armenian Hamster Anti-Mouse CD120α (Clone 55R-593) recognizes Mouse CD120α. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

    Background:

    Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-α and TNF-ß (also known as LT-α). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-?B induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.

    Host Species

    Armenian Hamster
    Formulation
    This antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
    Storage and Stability
    This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
    Reported Applications

    FC, N, IP

    Related Products
    Armenian Hamster IgG Isotype Control-Low Endotoxin Functional Formulation (Leinco Prod. No.: I-140)
    Anti-Mouse CD120α (TNFR1)-R-Phycoerythrin (Leinco Prod. No.: T247)
    Anti-Mouse CD120α (TNFR1)-Purified (Leinco Prod. No.: T246)