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 Anti-Mouse CD120α R-phycoerythrin (R-PE)(TNFR1)
  • Anti-Mouse CD120α R-phycoerythrin (R-PE)(TNFR1)
  • Anti-Mouse CD120α R-phycoerythrin (R-PE)(TNFR1)

    参考价格: ¥0.00
    适用范围:全领域
    所在地区:
    上架时间:2011年12月21日
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    详细说明

    Anti-Mouse CD120α
    R-phycoerythrin (R-PE)
    (TNFR1)
    Monoclonal Antibody
    Prod. No.: T247
    Clone: 55R-286
    Isotype: Armenian Hamster IgG
    Conc.: 0.1 mg/ml
    Pkg. Size: 50 μg, 500 μg

    Anti-Mouse CD120α
    R-phycoerythrin (R-PE)
    (TNFR1)
    Monoclonal Antibody
    Prod. No.: T247
    Clone: 55R-286
    Isotype: Armenian Hamster IgG
    Conc.: 0.1 mg/ml
    Pkg. Size: 50 µg, 500 µg

    Description
    Specificity:
    Armenian Hamster Anti-Mouse CD120α (Clone 55R-286) recognizes Mouse CD120α. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

    Background:

    Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-α and TNF-ß (also known as LT-α). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-?B induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.

    Reporter Molecule:

    R-phycoerythrin (R-PE) has a molecular weight of 240 kDa and is purified from red algae. R-PE is an intensely bright phycobiliprotein with an absorption maxima at approximately 496, 546 and 565 nm, and a fluorescence emission maximum of ~578 nm.

    Host Species

    Armenian Hamster
    Formulation
    This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
    Storage and Stability
    This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.
     
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