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Anti-Mouse CD120α(TNFR1)-R-Phycoerythrin

Anti-Mouse CD120α(TNFR1)-R-Phycoerythrin

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Anti-Mouse CD120αR-phycoerythrin (R-PE)(TNFR1)Monoclonal AntibodyProd. No.: T247 Clone: 55R-286 Isotype: Armenian Hamster IgG Conc.: 0.1mg/ml Pkg. Size: 50ug, 500ug

Anti-Mouse CD120αR-phycoerythrin (R-PE)(TNFR1)
Monoclonal Antibody
Prod. No.: T247
Clone:     55R-286
Isotype:   Armenian Hamster IgG
Conc.:     0.1mg/ml
Pkg. Size: 50ug, 500ug

Description
Specificity:
Armenian Hamster Anti-Mouse CD120α (Clone 55R-286) recognizes Mouse CD120α. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:
Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-α and TNF-ß (also known as LT-α). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-?B induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.

Reporter Molecule:
R-phycoerythrin (R-PE) has a molecular weight of 240 kDa and is purified from red algae. R-PE is an intensely bright phycobiliprotein with an absorption maxima at approximately 496, 546 and 565 nm, and a fluorescence emission maximum of ~578 nm.

Host Species
Armenian Hamster
Formulation
This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.
Country of Origin
USA
Related Products
Armenian Hamster IgG Isotype Control-R-phycoerythrin (Leinco Prod. No.: I-447)
Anti-Mouse CD120α (TNFR1)-Low Endotoxin Functional Formulation (Leinco Prod. No.: T245)
Anti-Mouse CD120α (TNFR1)-Purified (Leinco Prod. No.: T246)

Products are for research use only. Not for use in diagnostic or therapeutic procedures