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Anti-Mouse CD120α(TNFR1)-Purified

Anti-Mouse CD120α(TNFR1)-Purified

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Anti-Mouse CD120αPurified(TNFR1)Monoclonal Antibody Prod. No.: T246 Clone: 55R-286 Isotype: Armenian Hamster IgG Conc.: 2.0mg/ml Pkg. Size: 50ug, 500ug

Anti-Mouse CD120αPurified(TNFR1)
Monoclonal Antibody 
Prod. No.: T246
Clone:     55R-286
Isotype:   Armenian Hamster IgG
Conc.:     2.0mg/ml
Pkg. Size: 50ug, 500ug

Description
Specificity:
Armenian Hamster Anti-Mouse CD120α (Clone 55R-286) recognizes Mouse CD120α. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Background:
Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-α and TNF-ß (also known as LT-α). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-?B induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.

Host Species
Armenian Hamster
Formulation
This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This antibody is stable when stored at 2-8°C. Do not freeze.
Reported Applications
ELISA Det, FC, IP, WB

Related Products
Armenian Hamster IgG Isotype Control-Low Endotoxin Functional Formulation (Leinco Prod. No.: I-140)
Anti-Mouse CD120α (TNFR1)-Low Endotoxin Functional Formulation (Leinco Prod. No.: T245)
Anti-Mouse CD120α (TNFR1)-R-Phycoerythrin (Leinco Prod. No.: T247)

Products are for research use only. Not for use in diagnostic or therapeutic procedures