Anti-Mouse CD120αPurified(TNFR1)Monoclonal Antibody Prod. No.: T246 Clone: 55R-286 Isotype: Armenian Hamster IgG Conc.: 2.0mg/ml Pkg. Size: 50ug, 500ug
Prod. No.: T246
Isotype: Armenian Hamster IgG
Pkg. Size: 50ug, 500ug
Armenian Hamster Anti-Mouse CD120α (Clone 55R-286) recognizes Mouse CD120α. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-α and TNF-ß (also known as LT-α). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-?B induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.
This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Storage and Stability
This antibody is stable when stored at 2-8°C. Do not freeze.
ELISA Det, FC, IP, WB
Armenian Hamster IgG Isotype Control-Low Endotoxin Functional Formulation (Leinco Prod. No.: I-140)
Anti-Mouse CD120α (TNFR1)-Low Endotoxin Functional Formulation (Leinco Prod. No.: T245)
Anti-Mouse CD120α (TNFR1)-R-Phycoerythrin (Leinco Prod. No.: T247)
Products are for research use only. Not for use in diagnostic or therapeutic procedures