Anti-Mouse CD120αPurified Low Endotoxin Functional Formulation(TNFR1)Monoclonal AntibodyProd. No.: T245 Clone: 55R-593 Isotype: Armenian Hamster IgG Conc.: 1.0mg/ml Pkg. Size: Custom, 50ug, 500ug
Purified Low Endotoxin Functional Formulation
Prod. No.: T245
Isotype: Armenian Hamster IgG
Pkg. Size: Custom, 50ug, 500ug
Armenian Hamster Anti-Mouse CD120α (Clone 55R-593) recognizes Mouse CD120α. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-α and TNF-ß (also known as LT-α). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-?B induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.
This antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Storage and Stability
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
FC, N, IP
FC: This antibody can be used at a concentration of ≤ 1.0 µg per 100 µl of whole blood (or per 1.0 x 106 cells in a 100 µl total staining volume).
Each investigator should determine their own optimal working dilution for specific applications.
Country of Origin
Armenian Hamster IgG Isotype Control-Low Endotoxin Functional Formulation (Leinco Prod. No.: I-140)
Anti-Mouse CD120α (TNFR1)-R-Phycoerythrin (Leinco Prod. No.: T247)
Anti-Mouse CD120α (TNFR1)-Purified (Leinco Prod. No.: T246)
Products are for research use only. Not for use in diagnostic or therapeutic procedures