名称：原装订购| Recombinant Human IL-31
Source: E.coli. GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. Oncostatin M, LIF, and Cardiotrophin-1.
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases.
Description: Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). Measured by its ability to induce STAT3 activation in human U87 cells.