名称：原装订购| Recombinant Human IL-33
Source: E.coli. Recombinant human IL-33 is a 17.9 kDa protein containing 159 amino acid residues.
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses. Human IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family.
Description: It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. The ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107units/mg. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities.