名称：原装订购| Recombinant Murine IL-21
Source: E.coli. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells.
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses. Its action generally enhances antigen-specific responses of immune cells.
Description: IL-21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Determined by a cell proliferation assay using modified Ba/F3 cells. The expected ED50for this effect is 10-50 ng/ml.
The biological effects of IL-21 include induction of differentiation of T-cells-stimulated-B-cells into plasma cells and memory B-cells, stimulation (in conjunction) with IL-4 of IgG production, and induction of apoptotic effects in naïve B-cells and stimulated B-cells in the absence of T-cell signaling.