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 Recombinant Human sIL-4Rα
  • Recombinant Human sIL-4Rα
  • Recombinant Human sIL-4Rα

    参考价格: ¥2340.00
    品  牌:PeproTech
    产品型号:200-04R (15ug)
    所在地区:上海
    上架时间:2012年09月27日
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    Recombinant Human sIL-4Rα
    名称:原装订购| Recombinant Human sIL-4Rα
    货号:200-04R
    产地:PeproTech
    规格:15ug
    价格:2340
    Source: HEK293 cells. IL-4 can signal through type I and type II receptor complexes, which share a common γ chain (γc).
    Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses. The secreted extracellular domain of IL-4Rα, called sIL-4Rα, binds IL-4 and antagonizes its activity.
    Description: The type I receptor contains in addition to the γ chain an IL-4Rα subunit, whereas the type II receptor contains the IL-13Rα. The ED50 was determined by its ability to inhibit the IL-4 dependent proliferation of human TF-1 cells is ≤ 5.0 ng/ml (in the presence of 0.5 ng/ml of IL-4), It plays an important role in regulating the differentiation of naive CD4+ T cells and class switching to IgG1 and IgE.