上海叶舟生物科技有限公司

Recombinant Human IL-13

Recombinant Human IL-13

参考价格:¥2340.00
品  牌:PeproTech
产品型号:200-13 (10ug)
所在地区:华东 上海
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Recombinant Human IL-13
名称:原装订购| Recombinant Human IL-13
货号:200-13
产地:PeproTech
规格:10ug
价格:2340
Source: E.coli. Blocking of IL-13 activity inhibits the pathophysiology of asthma.  Human and murine IL-13 is cross-species reactive. 
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. 
Description: Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. The ED50 as determined by the dose-dependent proliferation of TF-1 cells was ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8.