名称：原装订购| Recombinant Human IL-16 (121 a.a.)
Source: E.coli. IL-16 also induces expression of IL-2 receptor (IL-2R) and MHC class II molecules on CD4 + T cells. Human and murine IL-16 show significant cross-species reactivity.
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses. IL-16 is a CD8+ T cell-derived cytokine that induces chemotaxis of CD4+ T cells and CD4+ monocytes and eosinophils.
Description: Analysis by gel filtration suggests that, under physiological conditions, hIL-16 exists predominantly as a noncovalently linked multimer, but that some IL-16 may exist as a monomer. Determined by its ability ot chemoattract human CD4+ T-Lymphocytes using a concentration range of 50.0-100.0 ng/ml. However, only the multimeric form appears to possess chemotactic activity, suggesting that receptor cross-linking may be required for activity.