名称：原装订购| Recombinant Human IL-20
Source: E.coli. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease.
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions.
Description: IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Determined by its ability to activate STAT following receptor ligand interaction. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β.