名称：原装订购| Recombinant Human IL-21
Source: E.coli. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells.
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses. IL-21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells.
Description: The biological effects of IL-21 include induction of differentiation of T-cells-stimulated B-cells into plasma cells and memory B-cells, Determined by its ability to induce human CD40L-activated naïve B cells to undergo Ig isotype switching to IgG, using an IL-21 concentration of 50 ng/ml. stimulation (in conjuction) with IL-4 of IgG production, and induction of apoptotic effects in naïve B-cells and stimulated B-cells in the absence of T-cell signaling.