名称：原装精品| Recombinant Human VCAM-1
Purity: Greater than 97% by SDS-PAGE gel and HPLC analyses.
Determined by its ability to support the adhesion of human U937 cells. VCAM-1 may play a vital role in the development several diseases, including atherosclerosis and rheumatoid arthritis.
The expected ED50 for this effect is 0.8-1.0 μg/ml. VCAM is a 110 kDa cell surface integral membrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules.
Synonyms: CD106, INCAM-100, MGC108734, MGC99561, VCAM, VCAM1, VCAM1B, VECAM1. Monomeric glycosylated VCAM-1 migrates at an apparent molecular weight of approximately 74.1kDa by SDS-PAGE analysis under reducing conditions.
Recombinant human VCAM-1 is a kDa glycoprotein comprising the extracellular domain (674 amino acid residues) of VCAM-1. Source: HEK293 cells. The primary function of VCAM-1 is the mediation of leukocyte-endothelial cell adhesion and signal transduction.
If you want to learn more about the product information, welcome to inquire!