名称：原装精品| Recombinant Human PECAM-1
Purity: Greater than 97% by SDS-PAGE gel and HPLC analyses.
Source: HEK293 cells
Determined by its ability to support the adhesion of activated Jurkat cells. Monomeric glycosylated PECAM-1 migrates at an apparent molecular weight of approximately 80.0-95.0 kDa by SDS-PAGE analysis under reducing conditions. The expected ED50 for this effect is 1.0 -1.5 μg/ml. It is highly expressed at endothelial cell junctions, and also expressed in platelets and in most leukocyte sub-types.
The primary function of PECAM-1 is the mediation of leukocyte-endothelial cell adhesion and signal transduction. Synonyms: Platelet endothelial cell adhesion molecule, CD31 antigen, EndoCAM. PECAM is transmembrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules.
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