名称：原装精品| Recombinant Murine SCF
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant murine SCF is an 18.3 kDa polypeptide containing 164 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF. Source: E.coli. The ED50 as determined by the dose-dependent stimulation of the proliferation of the human TF-1 cells is < 10 ng/ml, corresponding to a specific activity of > 1 x 105 units/mg. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells.
SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Synonyms: Stem Cell Factor,c-Kit Ligand,Mast Cell Growth Factor (MGF),Steel Factor. SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor.
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