名称：精品原装| Recombinant Human Leptin
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
PeproTechs human Leptin is biologically active in the ob/ob mouse obesity model. The ob/ob mice were treated via intraperitoneal injection once daily at a dose of 5 µg Leptin/gm of body weight for 7 days. Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Cross Reactivity: Chicken, Monkey, Mouse, Rat.
Recombinant human Leptin is a 16.0 kDa protein containing 147 amino acid residues. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline-treated controls. Synonyms: Obesity protein (OB).
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