名称：精品原装| Recombinant Human TIMP-2
Purity: Greater than 95% by SDS-PAGE gel and HPLC analyses.
Recombinant human TIMP-2 is a 21.8 kDa protein containing 194 amino acid residues. TIMP-2 activity was measured by its ability to inhibit human MMP-1 induced hydrolysis of a chromogenic peptide substrate at room temperature. TIMP-2 can also act through an MMP-independent mechanism inhibiting endothelial cell proliferation in vitro and demonstrates anti-angiogenic activities in vivo. Country of Origin: USA.
Source: E.coli. Half maximal inhibition was obtained at a TIMP-2 concentration of approximately 0.5 μg/ml, when using an MMP-1 concentration of 1.6 μg/ml. It belongs to the I35 (TIMP) family of irreversible protease inhibitors that function as key modulators of extracellular matrix degradation during tissue development and remodeling.
If you want to learn more about the product information, welcome to inquire!