名称：精品原装| Recombinant Human Resistin
Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant human Resistin is a 19.5 kDa disulfide-linked homodimeric protein composed of two identical 92 amino acid chains linked by a single disulfide bond. Determined by its ability to stimulate lipolysis in cultured human adipocytes. (Ort, T. et al. Endocrinology; 46(5):2200-9). Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis.
Source: E.coli. The three known members of this family; Resistin, RELM-α and RELM-β share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. Cross Reactivity: Mouse. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown.
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