上海叶舟生物科技有限公司

 Cyclosporin A
  • Cyclosporin A
  • Cyclosporin A

    参考价格: ¥1250.00
    品  牌:Sigma
    产品型号:C3662 (5MG)
    所在地区:上海
    上架时间:2012年09月27日
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    Cyclosporin A
    名称:正品现货|Cyclosporin A
    货号:C3662
    规格:5MG
    产地:Sigma
    CAS编号:  59865-13-3
    保存条件: RT
    biological source from Tolypocladium inflatum
    assay ≥95% (HPLC)
    form solid
    Gene Information human ... PPP3CA(5530), PPP3CB(5532), PPP3CC(5533), PPP3R1(5534), PPP3R2(5535)
    storage temp. 2-8°C
    相关信息: 中文名:环孢多肽A;环孢灵;环孢霉素A;赛斯平;山地明 ,环孢素,新山地明,环孢素A
    英文名:Ciclosporin A ,CsA, Cs-A, CY-A, Sandimmune, Ciclosporin, Cyspin.
    Sigma相关产品资料:
    CAS Number: 59865-13-3
    Linear Formula: C62H111N11O12
    Molecular Weight: 1202.61
    Beilstein Registry Number: 3647785
    Sigma C3662 Cyclosporin A
    from Tolypocladium inflatum, ≥95% (HPLC), solid
    Synonym: Antibiotic S 7481F1, Cyclosporine
    MDL number: MFCD00274558
    PubChem Substance ID: 24278028
    Description
    It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B). Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα. Can block cytochrome c release from mitochondria. Biochem/physiol Actions A fungal metabolite possessing potent immunosuppressive properties.
    Properties
    color white
    solubility dichloromethane: 10 mg/mL
      ethanol: 10 mg/mL
      DMSO: 50 mg/mL
      chloroform: 6 mg/mL
      H2O: insoluble