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 Phospho-IKK-alpha/beta (Ser176/180) (16A6) Rabbit mAb
  • Phospho-IKK-alpha/beta (Ser176/180) (16A6) Rabbit mAb
  • Phospho-IKK-alpha/beta (Ser176/180) (16A6) Rabbit mAb

    参考价格: ¥3487.00
    品  牌:CST
    产品型号:2697S
    所在地区:上海
    上架时间:2012年09月27日
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    Phospho-IKK-alpha/beta (Ser176/180) (16A6) Rabbit mAb
    名称:原装现货|Phospho-IKK-alpha/beta (Ser176/180) (16A6) Rabbit mAb
    货号:2697S
    规格:100ul
    产地:CST
    Source / Purification
    Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser176/180 of human IKKα. The key regulatory step in this pathway involves activation of a high molecular weight IκB kinase (IKK) complex whose catalysis is generally carried out by three tightly associated IKK subunits.
    Specificity / Sensitivity
    Activation of IKK depends upon phosphorylation of Ser177 and Ser181 in the activation loop of IKKβ (Ser176 and Ser180 in IKKα),
    Phospho-IKKα/β (Ser176/180) (16A6) Rabbit mAb detects IKKα only when phosphorylated at Ser176/180 and IKKβ only when phosphorylated at Ser177/181.