Storage:Desiccate at +4°C.
Solubility:Soluble to 100 mM in DMSO.
Prevents collagen- and thrombin-induced platelet aggregation, probably by blocking calpain induced phospholipase C and thromboxane synthase activation. Potent cathepsin L inhibitor.
Recently shown to preferentially inhibit a subset of protein-tyrosine phosphatases. Chemical Name: N-Benzyloxycarbonyl-L-leucylnorleucinal. Potent, cell-permeable inhibitor of the Ca2+-dependent protease, calpain.
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