Storage:Store at -20°C.
Solubility:Soluble to 2 mg/ml in 10% acetonitrile.
Blocks nicotinic-induced cationic signaling (IC50 ~ 200 - 250 nM) and inhibits nicotinic-agonist induced desensitization of catecholamine release. Alternative Name: Chromogranin A344-364.
Also stimulates mast cell release of histamine via a separate mechanism. Non-competitive nicotinic cholinergic antagonist; selectively inhibits nicotinic-stimulated catecholamine secretion from chromaffin cells and noradrenergic neurons (IC50 ~ 200 nM).
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