名称：正品现货|Bcl-xL (54H6) Rabbit mAb
Source / Purification
Bcl-xL prevents apoptosis through two different mechanisms: heterodimerization with an apoptotic protein inhibits. The antibody does not cross-react with other Bcl-2 family members. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Asp61 of human Bcl-xL.
Specificity / Sensitivity
its apoptotic effect (1,2) and formation of mitochondrial outer membrane pores help maintain a normal membrane state under stressful conditions (3). Bcl-xL is phosphorylated by JNK following treatment with microtubule-damaging agents such as paclitaxel, vinblastine and nocodazole (4,5). Bcl-xL (54H6) Rabbit mAb detects endogenous levels of total Bcl-xL protein.