Purity: >99% as evaluated by HPLC.
Molecular Formula: C28H26N4O3.
Molecular Weight: 466 g/mol.
Directions for Use
For a 1 mM solution, dissolve in 0.536 mL. It is a potent, cell permeable protein kinase C inhibitor with an IC50 of 0.7 nM. Dissolve the lyophilized alkaloid in DMSO or Methanol.
Staurosporine is an alkaloid isolated from the culture broth of Streptomyces staurosporesa. At 0.2- 1 μM, staurosporine induces cell apoptosis (2,3). At higher concentration (1-20 nM), staurosporine also inhibits other kinases such as PKA, PKG, CAMKII and Myosin light chain kinase (MLCK) (1).
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