上海叶舟生物科技有限公司

 (R,S)-Rolipram  正品原装
  • (R,S)-Rolipram  正品原装
  • (R,S)-Rolipram 正品原装

    参考价格: ¥4860.00
    品  牌:LC
    产品型号:R-2020 (300 mg)
    所在地区:上海
    上架时间:2012年09月27日
    留言咨询
    与企业取得联系时请告知该信息获取自中国教育装备采购网
    我要分享
    详细说明

    (R,S)-Rolipram  正品原装
    名称:原装进口| (R,S)-Rolipram
    产地:LC
    货号:R-2020
    规格:300 mg
    价格:4860
    储存温度说明
    Storage:  Store at or below -20 ºC. 
    Solubility:  Soluble in DMSO. 
    Disposal:  A.
    M.W. 275.34
     C16H21NO3
     [61413-54-5]
     M.I. 14:  8251
    产品其它相关介绍:
    View the MSDS for this product
    Parker, C.A., et al.  "Behaviour of [11C]R(-)- and [11C]S(+)-rolipram in vitro and in vivo, and their use as PET radiotracers for the quantificative assay of PDE4."  Rolipram suppressed cardiopulmonary bypass-induced systemic inflammatory response syndrome, probably through the regulation of proinflammatory mediators by inhibiting phosphodiesterase type 4.
    Synapse 55:  270-279 (2005). Rolipram is a selective phosphodiesterase 4 (PDE4) inhibitor.  PDE4 enzymes inactivate cyclic AMP (cAMP) via hydrolysis to 5-AMP. R-(-)-rolipram demonstrated a higher affinity for the PDE4 enzyme than S-(+)-rolipram, by about 8-fold in vitro and about 12- to 15-fold in vivo. 
    Rolipram has two enantiomeric forms, R(-) and S(+).  This product is the racemic mixture of the two enantiomers.  Hamamoto, M., et al.  "Suppressive effect of phosphodiesterase type 4 inhibition on systemic inflammatory responses after cardiopulmonary bypass."  J. Artif. Organs 9:  144-148 (2006). Rolipram reduced the initial and late response to ovalbumin (OVA) in isolated strips of guinea-pig colonic smooth muscle.
    我们的优势:
    我们的产品种类:品种齐全,价格合理!
    我们的承诺:
    我们的产品质量:绝无伪劣产品,质量有保障!