上海叶舟生物科技有限公司

 Brefeldin A
  • Brefeldin A
  • Brefeldin A

    参考价格: ¥5004.00
    品  牌:LC
    产品型号:B-8500 (100 mg)
    所在地区:上海
    上架时间:2012年09月27日
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    Brefeldin A
    名称:原装进口| Brefeldin A
    产地:LC
    货号:B-8500
    规格:100 mg
    价格:5004
    储存温度说明
    Storage:  Store at or below -20 ºC. 
    Solubility:  Soluble in DMSO at 100 mg/mL; soluble in ethanol at 25 mg/mL with slight warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 50-100 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility.  Disposal:  A. Brefeldin A, >99%. M.W. 280.36 C16H24O. Warning:  Toxic.
    产品其它相关介绍:
    View the MSDS for this product
    Specifically and reversibly blocks translocation of proteins from the endoplasmic reticulum to the Golgi apparatus. Brefeldin A has been identified as an activator of the sphingomyelin signal transduction cycle.
    Brefeldin A has been shown to induce apoptosis in human tumor cells via a process requiring caspase activation.  Misumi, Y., et al.  "Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes."  J. Biol. Chem. 261:  11398-11403 (1986). "The role of sphingomyelin cycle metabolites in transduction of signals of cell proliferation, differentiation and death." Guo, H., et al.  "Brefeldin A-mediated apoptosis requires the activation of caspases and is inhibited by Bcl-2."  Exp. Cell Res. 245:  57-68 (1998).
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    Brefeldin A