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Bryostatin 1  正品订购

Bryostatin 1 正品订购

参考价格:¥5364.00
品  牌:LC
产品型号:B-6697 (100 μg)
所在地区:华东 上海
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Bryostatin 1  正品订购
名称:Bryostatin 1
产地:LC
货号:B-6697
规格:100 µg
价格:5364
储存温度说明
Storage:  Store at or below -20 ºC.
Solubility:  Soluble in DMSO or ethanol.  Disposal:  A. Bryostatin 1, >99%. Note:  Binds to glass and plastic surfaces in aqueous solutions. M.W. 905.03. C47H68O17
产品其它相关介绍:
View the MSDS for this product
Bryostatin 1 fails to mimic many effects caused by PMA and actually blocks some PMA-induced response in a variety of cells and tissues. Kraft, A.S., et al. The correct molecular weight for bryostatin I is 905.04. "Bryostatin, an activator of the calcium phospholipid-dependent protein kinase, blocks phorbol ester-induced differentiation of human promyelocytic leukemia cells HL-60."
"Demonstration of sub-nanomolar affinity of bryostatin 1 for the phorbol ester receptor in rat brain."  Biochem. Pharmacol. 37:  4069-4073 (1988). Bryostatin 1 binds to and activates protein kinase C, but its biological effects differ greatly from those induced by other protein kinase C activators. Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use. The true affinity of bryostatin 1 for PDBu binding site on PKC appears to be in the low picomolar range or lower.  de Vries, D.J., et al. 
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