上海叶舟生物科技有限公司

 Epothilone B, Free Base
  • Epothilone B, Free Base
  • Epothilone B, Free Base

    参考价格: ¥3150.00
    品  牌:LC
    产品型号:E-5500 (10 mg)
    所在地区:上海
    上架时间:2012年09月27日
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    Epothilone B, Free Base
    名称:原装进口| Epothilone B, Free Base
    产地:LC
    货号:E-5500
    规格:10 mg
    价格:3150
    储存温度说明
    Storage:  Store at or below -20 ºC. 
    Solubility:  Soluble in DMSO at 40 mg/mL; soluble in ethanol at 40 mg/mL; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-50 µM buffers, serum, or other additives may increase or decrease the aqueous solubility.  Disposal:  A. Epothilone B, Free Base, >99%. M.W. 507.68 C27H41NO6S.
    产品其它相关介绍:
    View the MSDS for this product
    In contrast, the resistant cells retained sensitivity to epothilone B and the assembly was increased. Epothilones A-F are anticancer drugs.  They induce microtubule polymerization at submicromolar concentrations and lead to death of cancer cells. Purified tubulin from parental 1A9 human ovarian carcinoma cells demonstrated paclitaxel-driven increased polymerization while the resistant cell tubulin with a mutation at 270 (Phe --> Val) or 364 (Ala --> Thr) barely polymerized under identical conditions.
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