上海叶舟生物科技有限公司

Geldanamycin

Geldanamycin

参考价格:¥3478.00
品  牌:LKT
产品型号:G1646 (1 MG)
所在地区:华东 上海
留言咨询
与企业取得联系时请告知该信息获取自中国教育装备采购网
我要分享
详细说明

Geldanamycin
产品名称:Geldanamycin
产品货号:LKT  G1646
产品规格:1 MG
Description
A benzoquinoid ansamycin antibiotic having antitumor activities. It suppresses DNA replication by inhibiting c-myc gene expression in lymphoblastoma L5178Y cells. It inhibits tyrosine kinases and induces increased p53 protein involved in cell-cycle arrests of human ovarian tumor cells. It inhibits the 90 kDa heat shock protein that reglates cell signal transduction, and telomerase activity, and induces apoptosis.
Specifications 
Cas No. 30562-34-6
Product ID  G1646
Product Name  Geldanamycin
Synonym BRN 1633093
Formula Wt. 560.64
Melting Point 265
Purity ≥97% 
Solubility Soluble in DMSO.
Stability Protect from light.
Store Temp -20oC
References Yamaki H, Iguchi-Ariga SM, Ariga H. J Antibiot (Tokyo). 42:604-10 (1989). McIlwrath AJ, Brunton VG, Brown R. Cancer Chemother Pharmacol. 37:423-8 (1996). Villa R, Folini M, Porta CD et al. Carcinogenesis. 24:851-9 (2003). Kim S, Kang J, Hu W. Int J Can