上海叶舟生物科技有限公司

 Geldanamycin
  • Geldanamycin
  • Geldanamycin

    参考价格: ¥3478.00
    品  牌:LKT
    产品型号:G1646 (1 MG)
    所在地区:上海
    上架时间:2012年08月16日
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    Geldanamycin
    产品名称:Geldanamycin
    产品货号:LKT  G1646
    产品规格:1 MG
    Description
    A benzoquinoid ansamycin antibiotic having antitumor activities. It suppresses DNA replication by inhibiting c-myc gene expression in lymphoblastoma L5178Y cells. It inhibits tyrosine kinases and induces increased p53 protein involved in cell-cycle arrests of human ovarian tumor cells. It inhibits the 90 kDa heat shock protein that reglates cell signal transduction, and telomerase activity, and induces apoptosis.
    Specifications 
    Cas No. 30562-34-6
    Product ID  G1646
    Product Name  Geldanamycin
    Synonym BRN 1633093
    Formula Wt. 560.64
    Melting Point 265
    Purity ≥97% 
    Solubility Soluble in DMSO.
    Stability Protect from light.
    Store Temp -20oC
    References Yamaki H, Iguchi-Ariga SM, Ariga H. J Antibiot (Tokyo). 42:604-10 (1989). McIlwrath AJ, Brunton VG, Brown R. Cancer Chemother Pharmacol. 37:423-8 (1996). Villa R, Folini M, Porta CD et al. Carcinogenesis. 24:851-9 (2003). Kim S, Kang J, Hu W. Int J Can