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 Mdivi-1|BML-CM127-0010
  • Mdivi-1|BML-CM127-0010
  • Mdivi-1|BML-CM127-0010

    参考价格: ¥1134.00
    品  牌:Biomol
    产品型号:10 mg
    所在地区:上海
    上架时间:2018年08月28日
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    Mdivi-1|BML-CM127-0010
    产品名称:Mdivi-1
    规格:10 mg
    货号:BML-CM127-0010
    厂商:Biomol
    产品介绍:
    Mdivi-1 is a selective inhibitor of mitochondrial division in yeast and mammalian cells which acts via inhibiting the mitochondrial division dynamin. In cells, Mdivi-1 inhibits apoptosis by inhibiting mitochondrial outer membrane permeabilization. Mdivi-1 causes the rapid (<5 min) reversible and dose-dependent formation of net-like mitochondria in wild-type cells with an IC50= ~10µM. In yeast, time-lapse fluorescence microscopy revealed no detectable mitochondrial division after treatment with Mdivi-1.
    It inhibits Dnm1 GTPase activity in a dose dependent manner with an estimated IC50 of 1-10µM but is not a general inhibitor of GTPases.
    Product Specification
    Formula: C15H10Cl2N2O2S
    MW: 353.2
    Hazard: IRRITANT.
            TOXIC.   
    CAS: 338967-87-6
    Purity: ≥98% (TLC)
    Long Term Storage: -20°C 
    Appearance: White solid.
    Solubility: Soluble in DMSO (25mg/ml).
    Biomol Mdivi-1 BML-CM127-0010 10 mg -20°C 1134
    Biomol Mdivi-1 BML-CM127-0050 50 mg -20°C 4536