Sulfur containing antibiotic. Potent inhibitor of bacterial and yeast RNA polymerases. Inhibits mRNA chain elongation. Inhibits adhesion of endothelial cells (HUVECs) to vitronectin (IC50=0.83 µM) thereby inhibiting tumor cell-induced angiogenesis in vivo. Inhibits transcription in C. albicans. Inhibits microbiological growth in beer. Active against soil borne pathogens.
Purity: ≥ 98% (TLC)
Appearance: Yellow powder.
Long Term Storage: -20°C
Hazard: VERY TOXIC.
Solubility: Soluble in DMSO (5mg/ml), very slightly soluble in water
Source: Isolated from Streptomyces luteosporeus
Biomol Thiolutin BML-CT107-0001 1 mg -20°C 1407
Biomol Thiolutin BML-CT107-0005 5 mg -20°C 5670