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 Staurosporine|BML-EI156-0100
  • Staurosporine|BML-EI156-0100
  • Staurosporine|BML-EI156-0100

    参考价格: ¥1113.00
    品  牌:Biomol
    产品型号:100 ug
    所在地区:上海
    上架时间:2018年07月24日
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    Staurosporine|BML-EI156-0100
    产品名称:Staurosporine
    规格:100 ug
    货号:BML-EI156-0100
    厂商:Biomol
    产品介绍:
    Staurosporine inhibits a variety of kinases including PKA (Ki=7.0 nM), PKG (Ki=8.5 nM), MLCK (Ki=1.3 nM), PKC (Ki=0.7 nM), CaMK (IC50=20 nM), tyrosine kinases (IC50=70 nM) and phosphorylase kinase (IC50=0.5 nM). Inhibition is via interaction with the ATP binding site. It induces PKC translocation and augments PMA-induced ornithine decarboxylase. Activates a Bcl-2-regulated apoptosis pathway. At 1µM, induced apoptosis in CHO cells.
    Inhibits topoisomerase II directly by blocking transfer of phosphodiester bonds from DNA to active site tyrosine.
    Product Specification
    Formula: C26H26N4O3
    MW: 466.5
    CAS: 62996-74-1
    Formulation: Lyophilized.
    Purity: ≥99% (TLC)
    Long Term Storage: -20°C
    Appearance: Off-white to green powder
    Hazard: MAY BE CARCINOGENIC.TOXIC.
    Handling: Protect from light and moisture. 
    Use/Stability: Store, as supplied, at 0-4°C for up to 1 year. Store solutions at -20°C for up to 3 months.
    Solubility: Soluble in DMSO (25mg/ml), dimethyl formamide (25mg/ml), DMSO or ethyl acetate. Slightly soluble in chloroform and methanol. Insoluble in water.
    Biomol Staurosporine BML-EI156-0100 100 ug -20°C 1113
    Biomol Staurosporine BML-EI156-1000 1 mg -20°C 6846