Inhibits PKA and PKG selectively over PKC and MLCK. May be used in conjunction with H7 to probe for PKC-specific effects. Intracellular Ca2+ antagonist with no effect on cardiac function. Causes selective pulmonary vasodilation during pulmonary hypertension.
Alternative Name: N-(2’-Guanidinoethyl)-5-isoquinolinesulfonamide.HCl
Long Term Storage: -20°C
Handling: Protect from light.
Appearance: White to off-white solid.
Solubility: Soluble in water (40mg/ml).
Use/Stability: Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Biomol HA-1004 . HCl BML-EI184-0010 10 mg -20°C 1197
Biomol HA-1004 . HCl BML-EI184-0050 50 mg -20°C 4704