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  • Ub+1, pAb

    参考价格: ¥1365.00
    品  牌:Biomol
    产品型号:BML-PW9780-0025 (25 ul)
    所在地区:上海
    上架时间:2018年05月24日
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    Ub+1, pAb
    产品名称:NEDP1 (human), pAb
    规格:25 ul
    货号:BML-PW9775-0025
    厂商:Biomol
    产品介绍:
    Ub+1 is a novel form of ubiquitin that has been selectively observed in the brains of Alzheimers patients, including those with nonfamilial Alzheimers disease. Ub+1 is an efficient substrate for polyubiquitinylation in vitro and in transfected human cells. The resulting polyubiquitin chains are refractory to disassembly by deubiquitinating enzymes and potently inhibit the degradation of a polyubiquitinylated substrate by purified 26S proteasomes. Thus, expression of Ub+1 in aging brain could result in dominant inhibition of the Ub-proteasome system, leading to neuropathologic consequences.
    Product Specification
    Alternative Name: Ubiquitin+1
    Host: Rabbit
    Long Term Storage: -20°C
    Specificity: Recognizes human Ub+1.  
    Immunogen: Synthetic peptide corresponding to aa 76-95 of human Ub+1.
    Application: Immunohistochemistry Western Blot (1:1000)
    Optimal conditions must be determined individually for each application.
    Formulation: Liquid. In PBS containing 10mM sodium azide.
    Use/Stability: Store unopened vial at -20°C until required for use. The use of high quality antiserum-grade plastic or glass vials is recommended.. Dilute to working strength with phosphate buffered saline pH 7.2-7.4 and 1% normal goat serum (if a goat anti-rabbit IgG linker antibody is to be used). Store diluted antibody at 2-4°C (do not freeze) and use within 1 month.
    Handling: After opening, prepare aliquots and store at -20°C.
    Do not freeze.
    Biomol Ub+1, pAb BML-PW9780-0025 25 ul -20°C 1365
    Biomol Ub+1, pAb BML-PW9780-0100 100 ul -20°C 4767