上海浩然生物技术有限公司

 BAY 11-7085|BML-EI279-0010
  • BAY 11-7085|BML-EI279-0010
  • BAY 11-7085|BML-EI279-0010

    参考价格: ¥1155.00
    品  牌:Biomol
    产品型号:10 mg
    所在地区:上海
    上架时间:2018年08月28日
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    BAY 11-7085|BML-EI279-0010
    产品名称:BAY 11-7085
    规格:10 mg
    货号:BML-EI279-0010
    厂商:Biomol
    产品介绍:
    An irreversible inhibitor of cytokine-inducible IκBα phosphorylation (IC50=10 µM). In intact HUVECs it inhibits TNFα-induced phosphorylation and degradation of IκBα without affecting constitutive phosphorylation. Inhibition of IκBα phosphorylation and degradation results in the inactivation of NF-κB and NF-κB-dependent expression of endothelial-leukocyte adhesion molecules, E-selectin, VCAM-1 and ICAM-1. BAY 11-7085 displayed potent anti-inflammatory activity in the rat carrageenan paw edema assay and adjuvant arthritis model.
    Product Specification
    Formula: C13H15NO2S
    MW: 249.3
    Purity: ≥99%
    CAS: 196309-76-9  
    Appearance: White solid.
    Long Term Storage: Ambient
    Handling: Keep under inert gas.Protect from light.
    Solubility: Soluble in DMSO (>25mg/ml) or 100% ethanol (>25mg/ml). Insoluble in water.
    Biomol BAY 11-7085 BML-EI279-0010 10 mg Ambient 1155
    Biomol BAY 11-7085 BML-EI279-0050 50 mg Ambient 4578