规格: 100 UL BIOSOURCE (TM)
名称: CREB [PS133], Rabbit Polyclonal Antibody
cAMP responsive element binding protein (CREB) is a 43 kDa leucine zipper transcription factor that stimulates transcription and gene expression after it is phosphorylated on serine residues 129 and 133. CREB plays an important role in development, glucose homeostasis and growth-factor-dependent cell survival, and is implicated in learning and memory. The phosphorylation of CREB at serine 133 (PKA site) is essential for its transcriptional activity.
The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human CREB that contains serine 133. The sequence is conserved in mouse and rat.
Human and mouse CREB. Rat CREB (100% homologous) has not been tested, but is expected to react.
Human, Mouse, Rat
Hu, Ms (Rt)
RUO (Research use only)
For Research Use Only. Not for any animal or human therapeutic or diagnostic use.