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MDR1 VESICULAR ASSAY REAGENTS 原装正品

MDR1 VESICULAR ASSAY REAGENTS 原装正品

参考价格:¥4998.00
品  牌:invitrogen
产品型号:GM3030
所在地区:华东 上海
上架时间:2017-10-24
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MDR1 VESICULAR ASSAY REAGENTS 原装正品
产品: invitrogen
货号: GM3030
规格: 100 ASSAYS
名称: MDR1 Vesicular Transport Assay Reagent Set
The MDR1 Vesicular Transport Assay Reagent Set is a ready-to-use kit containing all reagents needed for vesicular transport assay except for the vesicles themselves. The reagent set can be used for vesicular transport assay using radioisotope-labeled or non-labeled compound. This kit has enough material to perform 100 vesicular transport assays.
• Investigate the transporter interactions of your drug candidates
• Assess potential for transporter-mediated drug-drug interactions
• Obtain high quality results with a large signal to noise ratios
Clear and Reliable Results
Prepared from Sf9 cells which have been engineered to over-express specific ABC transporters, these “inside-out" vesicles provide high levels of transporter activity with low background, giving you a clear signal if your compound is a substrate or inhibitor of a specific efflux transporter.
Kit Compatibility
Our MDR1 Vesicular Transport Assay Reagent Set is designed for use with MDR1 Vesicles. The 100 vesicular transport assays that can be performed with this kit will require two MDR1 Vesicle products
Concept Behind ABC Transporter Vesicles
ABC transporter vesicles are easy-to-use, efficient reagents for early assessment of a drug candidate’s substrate and drug interaction potential. While ABC transporters typically mediate the export of substrates out of cells, transporters expressed on these inside-out vesicles import substrates into the vesicles. It is therefore possible to quantitatively evaluate transport activity for your compound by determining the amount incorporated into the vesicles.
For Research Use Only. Not for any animal or human therapeutic or diagnostic use.