上海浩然生物技术有限公司

 siRNA plasmid pKD-Akt1/PKBα-v2 正品
  • siRNA plasmid pKD-Akt1/PKBα-v2 正品
  • siRNA plasmid pKD-Akt1/PKBα-v2 正品

    参考价格: ¥4129.00
    品  牌:millipore
    产品型号:62-041
    所在地区:上海
    上架时间:2018年11月01日
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    siRNA plasmid pKD-Akt1/PKBα-v2 正品
    产地: millipore
    货号: 62-041
    规格: 5 µg
    名称: siRNA plasmid, pKD-Akt1/PKBα-v2
    UniProt Summary: FUNCTION: SwissProt: P31749 # General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptotic effects of IGF-I. Mediates insulin-stimulated protein synthesis, partly by playing a role in both insulin-induced phosphorylation of 4E-BP1 and in insulin-induced activation of p70 S6 kinase. Promotes glycogen synthesis by mediating the insulin-induced activation of glycogen synthase.
    SIZE: 480 amino acids; 55686 Da
    SUBUNIT: Interacts with CENTG1 isoform 2 (PIKE-A) in the presence of guanine nucleotides. The C-terminus interacts with CCDC88A/GRDN. Interacts with AKTIP.
    SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Note=Nucleus after activation by integrin-linked protein kinase 1 (ILK1).
    TISSUE SPECIFICITY: In all human cell types so far analyzed.
    Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.