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4008190228-0529
 Akt/SGK Substrate Peptide 原装正品
  • Akt/SGK Substrate Peptide 原装正品
  • Akt/SGK Substrate Peptide 原装正品

    参考价格: ¥1829.00
    品  牌:millipore
    产品型号:12-340 (500 μg)
    所在地区:上海
    上架时间:2018年08月28日
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    Akt/SGK Substrate Peptide 原装正品
    产地: millipore
    货号: 12-340
    规格: 500 µg
    名称: Akt/SGK Substrate Peptide
    Key Applications: Kinase Assay
    Entrez Gene Summary: The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene.
    Usage Statement: Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.