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 FlowCellect MAPK Activation Dual Detection Kit 原装正品
  • FlowCellect MAPK Activation Dual Detection Kit 原装正品
  • FlowCellect MAPK Activation Dual Detection Kit 原装正品

    参考价格: ¥3450.00
    品  牌:millipore
    产品型号:FCCS025106 (25 Tests / Kit)
    所在地区:上海
    上架时间:2018年11月01日
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    FlowCellect MAPK Activation Dual Detection Kit 原装正品
    产地: millipore
    货号: FCCS025106
    规格: 25 Tests / Kit
    价格/元:3450
    名称: FlowCellect™ MAPK Activation Dual Detection Kit 原装正品
    Key Applications: Flow Cytometry
    Species Reactivity: Human
    Background Information: Erk (Extracellular signal-Related Kinase) is a family of two, highly homologous proteins denoted as Erk1 (p44, MAPK3) and Erk2 (p42, MAPK1) that both function in the same pathway. The two proteins are often referred to collectively as Erk1/2 or p44/p42 MAP kinase. The Erk pathway is considered the classical, canonical MAPK (Mitogen-Activated Protein Kinase) signaling pathway. It is an evolutionarily conserved pathway that controls and is a critical regulator of the growth and survival through the promotion of cell proliferation and the prevention of apoptosis. Erk is involved in the control of many fundamental cellular processes including cell proliferation, survival, differentiation, apoptosis, motility and metabolism. Erk is activated by growth factor stimulation of receptor tyrosine kinases (RTKs), GPCR, and/or integrin stimulation. This activates the Ras-Raf-MEK-Erk pathway that results in the phosphorylation/activation of Erk1/2 (p44/p42) on the TxY motif (Thr202/Tyr204 and Thr185/Tyr187 for Erk1 & Erk2, respectively).
    Components:
    1. 20X Anti-phospho-ERK1/2 (Thr202/Tyr204, Thr185/Tyr187) PE Conjugated Antibody: (Part No. CS203329) One vial containing 150 µL.
    2. 20X Anti-ERK1/2-Alexa Fluor® 647 Conjugated Antibody: (Part No. CS205075) One vial containing 150 µL.
    3. Fixation Buffer: (Part No. CS202122) One bottle containing 13 mL.
    4. 10X Wash Buffer: (Part No. CS202123) One bottle containing 13 mL.
    5. 5X Assay Buffer: (Part No. CS202124) One 55 mL bottle
    6. 1X Permeabilization Buffer: (Part No. CS203284) One bottle containing 13 mL.
    Storage Conditions: 4-8°C for antibodies and buffers

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