产品名称：ADENOPHOSTIN A, HEXASODIUM SALT
One of the most potent known agonist of type 1 inositol 1,4,5-trisphosphate receptor (InsP3R; EC50 = 10.9 nM). Exhibits about 50- to 100-fold greater affinity for IP3R than IP3. Stimulates Ca2+ release from Ins(1,4,5)P3-sensitive Ca2+ stores in microsomal preparations, permeabilized cells, and lipid vesicles containing purified InsP3R (EC50 = 14.7 nM for Ca2+ release from permeabilized hepatocytes). Does not bind to Ins(1,3,4,5)P4 binding sites and is resistant to enzymatic degradation.
Molecular Weight: 801.2
Presentation: White solid.
Storage Conditions: Shipped at Ambient Temperature. Store at -20°C.
Purity: ≥90% by HPLC
Empirical Formula: C16H20N5O18P3 · 6Na
Properties: Solubility: H2O (1 mg/ml).