Background Information: An agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex. Mimics the effects of glycine on the NMDA receptor ion channel and blocks 3H-glycine binding to rat forebrain membrane (IC50 = 38 nM). Blocks NMDA-induced release of arachidonic acid (IC50 = 131 µM) in cerebellar granule cells. Reduces NMDA-induced cell death in hippocampal neurons.
Molecular Weight: 101.1
Presentation: Crystalline solid.
Properties: Solubility: H2O (40 mg/ml). May require heating and sonication to achieve complete solubilization.
Purity: ≥ 98% by TLC
Empirical Formula: C4H7NO2
Storage Conditions: Shipped at Ambient Temperature. Store at +15 - 30°C.