上海浩洋生物科技有限公司

 CDC25 PHOSPHATASE INHIBITOR I, BN82002
  • CDC25 PHOSPHATASE INHIBITOR I, BN82002
  • CDC25 PHOSPHATASE INHIBITOR I, BN82002

    参考价格: ¥1689.00
    品  牌:merck
    产品型号:217691-5MG (5MG)
    所在地区:上海
    上架时间:2013年04月23日
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    CDC25 PHOSPHATASE INHIBITOR I, BN82002
    产品名称:CDC25 PHOSPHATASE INHIBITOR I, BN82002
    产品货号:217691-5MG
    产品价格:¥1689
    产品规格:5MG
    Background Information: A cell-permeable ortho-hydroxybenzylamino compound that displays antitumor properties. Acts as a potent, selective and irreversible inhibitor of CDC25 phosphatase family (IC50 = 2.4, 3.9, 6.3, 5.4, and 4.6 µM for 25A, 25B2, 25B3, 25C, and 25C-cat, respectively). Displays ~20-fold greater selectivity for CDC25 phosphatases over CD45 tyrosine phosphatase. Shown to delay cell cycle progression in vitro (IC50 = ~7.2-32.6 µM), and reduces tumor growth in athymic mice xenografted with the human pancreatic cells MIA PaCa-2 (15 mg/kg, i.p. route).
    Empirical Formula: C19H25N3O4
    Properties: Solubility: DMSO (10 mg/ml) or Ethanol (10 mg/ml).
    Presentation: Brown solid. Packaged under inert gas.
    Storage Conditions: Shipped at Ambient Temperature. Store at -20°C.